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In UC mice, glutamine (Gln) reduced oxidative stress-induced injury by inhibiting the PI3K/Akt signaling pathway (169)

BMJ 2014;349:g5226

Neuromelanin (NM), a dark pigment present in dopaminergic neurons of the SN, increases during development and stabilizes in midlife but declines after 60 years of age (264)

Although dietary lipids encompass triacylglycerols, phospholipids, sterols (predominantly cholesterol with minor phytosterols), and small amounts of free fatty acids 10,11 only fatty acyl chains are oxidizable for yielding energy, whereas cholesterol is catabolized chiefly to bile acids rather than used as an energy substrate 12

KCs ferroptosis is generally considered to promote disease progression