Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan maleimide CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOCCOCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95%

CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOCCOCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

586 Purity (HPLC) >= 95% Solubility DMSO

Product Name Thalidomide-O-PEG4-OH Synonyms Thalidomide-4'-O-PEG4-OH CAS Number 2415370-32-8 Related CAS Molecular Formula C21H26N2O9 Molecular Weight 450

SiR-Azide is a far-red fluorescent probe containg azide moiety for click chemustry apploications

Product Name Lenalidomide-PEG3-OH Synonyms Lenalidomide-4'-PEG3-OH CAS Number n/a Related CAS Molecular Formula C19H25N3O6 Molecular Weight 391

Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan maleimide CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOCCOCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is