Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB dbco-maleimide monosulfo is azide-activated fluorescent dyes

monosulfo is azide-activated fluorescent dyes for chemoselective labeling and detection of alkyne-tagged molecules

NRX-252114 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta-catenin by the 26S proteasome

In click chemistry

The activities of SNAP-tag and H5 enzymes on BGSN3 are reasonable (IC50=17

1038/nchem

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB dbco-maleimide monosulfo is azide-activated fluorescent dyesSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine