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469 The mitochondrial protein sideroflexin 1 (SFXN1) is responsible for importing iron from the cytoplasm to the mitochondria, and SFXN1 deficiency leads to mitochondrial respiratory chain damage, affecting the biogenesis and assembly of complex III

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To ensure the vehicle alone did not cause estrogenic effects, a DMSO treatment (0.0003%) was included for each analysis

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Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice