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The tumor suppressor OTUD1 interacts with and promotes deubiquitination of IREB2 (iron-responsive element-binding protein 2), stabilizing IREB2 and activating downstream TFRC gene expression

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Their peptide levels matter too

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This dual-pathway interest has contributed to the growing use of this blend in research examining coordinated peptide activity, receptor crosstalk, and intracellular signaling frameworks