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IHC levels of Ki-67 and PHH3 also were significantly higher in atypical PN

Its preservative agent (benzyl alcohol) is essential for preventing microbial growth after the stopper has been punctured

Further, microneedling procedures facilitate drug penetration through the stratum corneum [161]

A key element in assessing the benignity of a melanocytic lesion is to determine the presence of maturation, i.e., the tendency to undergo a morphologic shift with progressive depth in the dermis as seen on both light microscopy and immunohistochemical expression