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How phenotypic screening influenced drug discovery: Lessons from five years of practice

However, mTORC1 is not equally sensitive to all AAs

Induces oxidative stress (a) Humans (i) Exposed humans No data on induction of oxidative stress in humans were available to the Working Group

The PDO-based metabolic drug screening platform is becoming an essential tool for the development of personalized strategies [179]

This work was supported by Research Foundation Flanders (G089818N & G039821N), Excellence of Science Grant EOS 30446199 (MEMODYN), and the KU Leuven Research Fund C16/15/070, awarded to SS and coworkers