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Monitor Tolerance: Regular smokers may need T-breaks to maintain effectiveness

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Sample size and participants The sample size was calculated according to a rate of smoking in the last 12 months of 34% in the control group based on data from the ESTUDES 20162017 survey 4 and assuming a 20% rate in the intervention group, with an alpha level of 0.05 and 80% statistical power, giving a total of 141 students per group necessary

And they may cause dangerous internal bleeding