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It was observed that the cigarette smoke treated group demonstrated an elevated number of total leukocytes, lymphocytes, macrophages and neutrophils compared with the animals exposed to fresh air (control group)

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Conflicting with the above described human findings, daily pre-session administration of 30 mg/kg bupropion in adult rats tend to increase nicotine self-administration (Shoaib et al., 2003

The study estimated doses through inhalation and dust ingestion using TSNA indoor concentrations measured by Consortium investigators and other authors