Et des indices manant de la recherche pharmacologique et les informations gnres par les utilisateurs et par l'industrie laissent penser que ces additifs WS-23/WS-3 gnrent des sensations de refroidissement agrables qui masquent la duret de la nicotine tout en manquant de certaines caractristiques aversives des produits uniquement menthols [88]
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A comprehensive federal study conducted by the National Academy of Sciences Institute of Medicine arrived at a similar conclusion: "Millions of Americans have tried marijuana, but most are not regular users [and] few marijuana users become dependent on it [A]lthough [some] marijuana users develop dependence, they appear to be less likely to do so than users of other drugs (including alcohol and nicotine), and marijuana dependence appears to be less severe than dependence on other drugs." Alcohol use increases the risk of injury to the consumer
