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Since tobacco use is driven by nicotine addiction, researchers who study tobacco control, like the University of Waterloos David Hammond, told me, [This] would be one of the most significant tobacco control measures ever undertaken. (Its also an approach clinical trial data suggests helps wean people off smoking.) The move is unprecedented no other country has attempted to limit the nicotine content in cigarettes and it would likely affect every brand of conventional cigarette on the market, Hammond said

Despite the well-established global understanding that tobacco is a lethal substance, some individuals find it challenging to completely quit, posing significant risks not only to their personal health but also to the well-being of their loved ones

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However, there was barely study about the effect of smoking on infective endocarditis regarding oral microbiome

This is due to the notion of placental accumulation, as the placenta serves as a passage for the entry of nicotine (and other chemicals found in cigarettes) into the fetal compartment, through both passive diffusion and active transport [13, 14]