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In one study, emphysema-resistant (ICR) and emphysema-sensitive (C57BL/6) mouse strains showed differences in BAL cytokine and chemokine responses following a nose-only inhalation exposure to 2R1 reference cigarette mainstream smoke (two-second, 35-mL puff, once per minute) for two hours per day for seven days (Obot et al

Quitting remains the only way to eliminate tobacco-related health risks entirely

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But participants who both smoked and vaped were no less likely to show these biomarkers than participants who exclusively smoked traditional cigarettes