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The data table additionally provides details regarding the comparison group, smoking habits (if assessed), the pharmaceutical molecule studied, a description of the intervention and its outcomes, the postulated pharmacokinetic and pharmacodynamic mechanisms, the enzymes involved in the metabolism of drugs and affected by smoking, studied in each included article and the major findings for each study included

Insurance companies also take that into consideration and treat you the same as traditional smokers

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Hence, one might postulate that given the potentially large effect size of the aforementioned factors associated with both smoking status and IBD, that the magnitude of any direct mechanistic or toxic effect of smoking constituents on the intestinal milieu or treatment(s) might in fact be dwarfed by these cofactors, as represented in Fig