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Across the UK, enforcement action against illegal tobacco and vape sales has led to seizures, prosecutions and business closures, highlighting the wider impact of this criminal trade

As of last year, the company's smoke-free portfolio accounted for about 29% of its net revenue, or $31.4 billion

Informed of typical withdrawal symptoms, which can be quite intense during the first few weeks of tobacco abstinence and supported with developing coping strategies

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The smokingrelated prostate cancer data analyzed in this study were obtained from GBD 2021, which are derived from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, satellite imaging, and disease notifications, and provide the burden of 371 diseases and injuries in 21 GBD regions and 204 countries and territories over the period 1990 to 2021 (included 32 time points) from updated epidemiological data estimates 12-15