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Provide its own antioxidant support in the brain

There were significant differences in body mass index, hepatobiliary enzymes, lipids, glucose, smoking and fast eating between participants with and without NAFLD onset

Thus, alcohol affecting the central clock can create favorable conditions for its toxic effects and the development of liver disease

Pattern recognition receptors (PRRs), including Toll-like receptors (TLRs) and NOD-like receptors (NLRs), sense microbial components and damage-associated molecular patterns (DAMPs), triggering activation of signaling cascades such as NF-B, MAPK, and inflammasomes (e.g., NLRP3), which further amplify the inflammatory response [40]

Mitophagy Although MLCS represents a novel mechanism of organelle crosstalk that is independent of mitophagy, studies have indicated that these contacts are linked to mitophagy (Juhl et al., 2021