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Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents

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Ismail SN, Ladius C, Abidin EZ, Samah MA, Sulaiman FR

Researchers from the National Institute on Drug Abuse, National Institutes of Health, and Case Western Reserve University School of Medicine used a target trial emulation framework to evaluate the comparative effectiveness of the new use of semaglutide versus the new use of 7 other anti-diabetes medications, including other GLP-1RAs, on TUD-related health care measures in 3 study populations: patients with comorbid type 2 diabetes and TUD, patients with comorbid type 2 diabetes and TUD who had a diagnosis of obesity, and those who did not have a diagnosis of obesity