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Risk of Heart Failure and Death After Prolonged Smoking Cessation Circulation: Heart Failure Smoking, Alcohol and Heart Disease, the Dangerous Connection. Blog Male Excel Smoking and Heart Health StoryMD What cigarettes do to your heart SMOKING & YOUR HEART: 1 Nicotine: Spikes adrenaline, raising HR BP. 2 CO: Blocks oxygen, overworking the heart. 3 Inflammation: Causes plaque buildup clots. 4 Vessel Damage: Leads to hypertension. Result: High risk of
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