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RRs increased in all sex-ethnicity groups

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Competition from adjacent harm-reduction categories, including chewing tobacco products designed as cigarette substitutes and next-generation nicotine products, creates substitution risk in consumer segments motivated primarily by harm reduction rather than specifically seeking herbal or natural alternatives

In contrast, the eastern regions of Crete, such as the Heraklion and Lasithi prefectures, are often more affordable

"Light" cigarettes provide no significant health benefits, as smokers often compensate by inhaling more deeply or smoking more