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The moderating effect of OPRM1 is an exploratory aim given that: (i) there have been several investigations of the moderating role of this SNP on naltrexone in alcohol patients and (ii) the prevalence of Asp40 carriers is 1525% and potential under-sampling will, thus, reduce the power to test the effect

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While young people overwhelmingly see through Big Tobacco and its attempts to lure them in, they are using tobacco products at rates unseen in years, revealing how powerful, persuasive and addictive the industry and its products are