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Cigarettes also contain fillers made from stems and other parts of the tobacco pants that are mixed with water, flavorings, and additives

The recruited macrophages release cytokines, such as tumor necrotic factor-alpha (TNF-), interleukin-1 (IL-1), and interleukin-8 (IL-8)

Available at: apps.who.int/iris/bitstream/handle/10665/255692/9789241512671eng.pdf;jsessionid=4D9E6E1D4311C4B05E87BD2424AF3822?sequence=1

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North American moist snuff markets, centered on traditional consumers primarily in rural and mid-Western demographic segments, sustain demand for flavored variants despite regulatory pressures