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This can be confused with a well-differentiated squamous cell carcinoma, especially in a superficial biopsy specimen PAS, S-100, and myelin basic protein stains are positive in the granular cytoplasm Angiokeratoma Clinical Angiokeratomas are vascular lesions and occurs almost exclusively on vulva of the child-bearing women The cause is unknown, but a patient with multiple angiokeratomas on the vulva and other sites should receive consultation for Fabry disease, which is an X-linked recessive disease associated with a deficiency of galactosidase A Patients are usually asymptomatic
Smoking is one of the leading causes of preventable deaths worldwide, and it has been linked to numerous health problems, such as lung cancer, heart disease, stroke, and respiratory diseases
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