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In 2016, before the legislation was introduced, more than three quarters of current or former vapers surveyed by ASH vaped liquids with concentrations of nicotine of 18 mg/ml or less (77%), with nearly half (49%) using e-liquid containing 12 mg/ml or less

Additionally, aerosolized nicotine from vaping has been linked to increased thromboembolic activity and impaired dilation and relaxation of small blood vessels ( Given the ongoing debates about the health implications of electronic cigarette use, this systematic review aims to thoroughly investigate the direct effects of electronic cigarette use on human health, considering the characteristics of the populations studied and the duration of exposure