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Several other studies, [97-101] including a meta-analytic review [98] and a retrospective study, [97] suggested that stimulant therapy in childhood is associated with a reduced risk of subsequent substance use, cigarette smoking and alcohol use disorders

As Duke of Gloucester in his early 20s, Richard III was given many responsibilities by his brother, becoming a powerful landowner and political force to be reckoned with in the north, further establishing his future reign as King of England

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