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These 227 participants were then split into four groups based on their behavior: people who are light dual users, predominantly vapers, heavy dual users, and predominantly smokers

OSF is characterized by inflammation, heightened deposition of submucosal collagen, and the development of fibrotic bands in the oral and para-oral tissues, progressively limiting mouth opening [14]

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Finally, both analyses were run for the entire data and for temperate regions only, where most of our data come from (Fig