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059) joyned as together with the colonie it must rise and faile, grow and impair, and that not a small matter neither, but of twenty thousand pounds per annum, (for the offer of so much in certainty hath his majestie been pleased to refuse in favor of the Plantations)." On Friday the 22d of March 1622 the Indians attacked the plantations "and attempted in most places under the color of unsuspected amytie, and by surprise to have cut us all off and to have swept us all away at once throughout the whole lande had itt not pleased God of his abundant mercy to prevent them in many places, for which we can never sufficient magnifie his blessed, name." But notwithstanding this terrible massacre in which nearly four hundred persons were slain the colony increased in wealth and numbers as plantations were laid out and the colonists developed the various resources of the country

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The COVID vaccines led to a substantial reduction in hospitalization and death from the disease, according to peer-reviewed studies

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