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Consider Brain-Supportive Nutrients While theres no magic bullet, certain nutrients show real promise for supporting cognition especially when combined with lifestyle upgrades.(6) Here are some that stand out: Omega-3 fatty acids (especially DHA): support neuron structure and reduce inflammation Phosphatidylserine: aids memory and cell signaling Acetyl-L-carnitine: supports mitochondrial energy in neurons Lions Mane mushroom: may stimulate nerve growth factor Curcumin: crosses the blood-brain barrier and combats inflammation B-complex vitamins (especially B6, B12, folate): lower homocysteine, a known neurotoxin(12) Vitamin D: low levels have been linked to increased risk of cognitive decline Ask your healthcare provider to test for deficiencies before supplementing especially B12 and D