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Signs and Symptoms of Addiction to Cigarettes and Alcohol Cigarette Addiction: Strong cravings for nicotine due to cigarette smoking Smoking despite health issues Irritability and anxiety when not smoking Difficulty quitting despite multiple attempts Increased tolerance, needing more to feel satisfied Alcohol Addiction: Drinking more or longer than intended Loss of control over alcohol use Withdrawal symptoms (shaking, nausea, anxiety) Neglecting responsibilities due to drinking Needing more alcohol to feel the effects Both addictions can severely impact health and daily life

Content validityestablishing and reporting the evidence in newly developed patient-reported outcomes (PRO) instruments for medical product evaluation: ISPOR PRO good research practices task force reportPart 2assessing respondent understanding

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This material is also used to produce photographic film and acts as a component in eyeglass coatings