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found that TFPs significantly mitigated HFD-induced obesity in mice (41)

Refractive power and biometric properties of the nonhuman primate isolated crystalline lens

Less direct evidence comes from observations that mice with mutations of the POLG gene, which encodes a subunit of mtDNA polymerase, exhibit depression-like symptoms (Kasahara et al., 2006), and that polymorphisms of genes that code for mitochondrial enzymes, such as MTHFD1L, are associated with negative rumination, which is a precursor to depression (Moustafa et al., 2014)

For example, ferroptotic airway epithelial cells release HMGB1, which activates M1 macrophages via the TLR4 pathway (136)

10.1007/s10815-020-01909-0 61 IriawatiI.VitasastiS.RahmadianF