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Second is their balance of well-studied anxiolytic botanicals included alongside cannabinoids: 30mg CBD: a low dose, but clinically relevant for sleep complaints2 20mg CBN: the exact dose shown in a 2024 study to reduce nighttime wakefulness and overall sleep disturbance without resulting in next-day grogginess29 300mg lemon balm: just shy of the 320mg dose shown to improve sleep quality and restlessness6 120mg passionflower: shown in a 2020 placebo-controlled study to improve total sleep time and sleep efficiency at doses as low as 60mg25 120mg Shoden ashwagandha: a potent branded form of a well-known anxiolytic, capable of promoting sleep via stress relief at a 120mg dose24 Compare this ingredient list to, say, Slumber and CBDistillery, which rely entirely on cannabinoids for their sleep-promoting action

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Nicotine and pathological angiogenesis