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Thus, the cells relied on the accumulated GSH prior to SSF to relieve the toxicity

It is therefore reasonable to assume that the infiltered CD8 + T cells should exhibit properties of activation (expression of PD-1) or activation leading to exhaustion (expression of PD-1, LAG3, TIM3 and CTLA-4)

Bile salts are the primary driver of bile flowing from the liver into the gallbladder and out into the small intestine