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Arkan Sayed-Noor said, Smoking appears to be a risk factor for developing lower spine space narrowing that can lead to surgical treatment. Herniated Disc While discs often degenerate as we age, nicotine can reduce blood flow and further contribute to degenerative disc disease

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Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: evidence for variable homozygous deletions in the Parkin gene in affected individuals