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However, we aimed to avoid over-adjustment and multicollinearity by selecting a limited number of covariates that were both theoretically justified and available across the full time series

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Second-hand smoke and COPD Exposure to second-hand smoke is a significant risk factor for the onset and progression of COPD

COPD is also the third-leading cause of death globally 2 and is projected to increase in the next 40 years, leading to approximately 5 million deaths each year 3