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Mild short-term side effects of Adderall include: Dry mouth Headaches Dizziness or nausea Sleeping problems Loss of appetite Weight loss Anxiety More serious but generally still short-term side effects of Adderall include: Irregular heartbeat High blood pressure Impaired thinking Aggressive behavior Long-Term Effects of Smoking Adderall Aside from short-term adverse effects, misusing Adderall may also lead to long-term effects or cause permanent changes to your body