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In addition, pharmacists in Malaysia could prescribe NRT products, and when they led a smoking cessation service, it was more successful than other smoking cessation trials in Malaysia

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Since 2003, the total disease burden attributable to tobacco use has substantially decreased (by 41%) and it was found to be the second leading risk factor contributing to the total disease burden in 2024, behind overweight/obesity

Co-administration of an OCT2 inhibitor, cimetidine (300 mg four times daily), with varenicline (2 mg single dose) to 12 smokers increased the systemic exposure of varenicline by 29% (90% CI: 21.5%, 36.9%) due to a reduction in varenicline renal clearance