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Although the research did not give a physiological explanation for the results, Silverstein said that since nicotine and smoking harm the vascular system, the study suggests they also damage blood vessels and neurons in the retina

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Common compliance elements include: Health warning labels, often covering a large percentage of the pack surface Plain packaging rules in some countries, limiting branding and imagery Mandatory legal text, including tax stamps or duty-paid markings where required Barcodes and traceability markings for supply chain tracking Age restriction notices, where legally required Country-specific labelling rules, which differ significantly by market Because these requirements change and vary by jurisdiction, always verify current regulations with the relevant local authority before producing or selling tobacco packaging