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Single-cell omics unveils molecular lineages and remodeling mechanisms of the small airways In small airway stenosis, fibroblast-driven ECM remodeling is the core of structural stenosis, while persistent inflammation dominated by neutrophils and macrophages provides the cellular and enzymatic basis for this process (such as MMPs and ROS), promoting the degradation and redeposition of ECM (67, 68)

To verify the data obtained from the topography device, participants will self-report the number of cigarettes they smoked during the 24-hour pack exposure, details of any cigarettes not smoked from the pack given to them or through the monitor, and any unusual events about the previous day (other than taking part in the experiment) which may have changed their smoking behavior

Nicotine poisoning often causes nausea, vomiting, dizziness, tremors (shakiness), and sweating, and can make the heart beat much faster than normal

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17385S0401, Junsei, Tokyo, Japan) solution (pH 7.8) for 3 weeks