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WT p53 inhibited Parkin translocation and subsequent mitophagy, whereas a p53 form locked into the nucleus (using a disrupted nuclear export signal, NES) and an endoplasmic reticulum (ER)-targeted p53 (p53 ER) failed to inhibit the process of mitophagy

4) Tobacco paste treatment is an old traditional healing use for insect stings including wasps, hornets, fire-ant, scorpions and bee-stings and involves the mashing of tobacco in water to make a paste which is then applied onto the area like a poultice and remission is said to occur in 20-30 minutes

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