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Tobacco: Its historical, cultural, oral, and periodontal health association PMC Smoking has a significant, well documented negative effect on wound healing. How Smoking Affects Wound Healing 1. Reduced Oxygen Delivery Nicotine causes blood vessels to constrict. Carbon Dr. S.0 MIKAYE Nicotine Addiction & Vascular Health: Link to Varicose Veins Dr. Does Every Cigarette Puff Damage Your Bones? Tobacco may feel like just a habit, but it quietly damages your body at a cellular level. Smoking causes vasoconstriction, which is the Effects of Nicotine Contained in Tobacco Mainstream Smoke on Vascular Smooth Muscle Cells IntechOpen

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