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Monte Carlo simulations were performed with 10,000 iterations using Latin Hypercube sampling and Mersenne Twister random number generator

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A trial conducted by Georgetown University tested eight sessions of telephone counseling and 8 weeks of NRT patches without other pharmacotherapy. Cessation rates of 14.3% at 3 months and 10.3% at 6 months are encouraging given that 48% of participants in the trial were not yet ready to quit at the time of enrollment