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Nicotine pharmacokinetic profiles of the Tobacco heating System 2.2, cigarettes and nicotine gum in Japanese smokers

According to previous studies on the microbial community in tobacco showed that the dominant microorganism on the surface of tobacco was mainly Bacillus , which plays a key role in the degradation of macromolecules to increase aroma content and improve tobacco quality during the natural tobacco fermentation (Wang et al

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