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None of these organizations played any role in the preparation of this paper or the decision to submit it for publication

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Disruption of intracellular homeostasis, such as endoplasmic reticulum (ER) stress, impairment of mitochondrial and lysosomal function, and dysregulation of lipid metabolism and signaling between the ER and mitochondria, leads to the acceleration of -Syn accumulation, Lewy body formation, and neuronal cell death (Bloem et al., 2021)

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