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Adderall is a stimulant and alcohol is a depressant, so using both at the same time is not recommended because it can mask the feelings of intoxication and may put significant stress on the heart and cardiovascular system

6 A 2019 randomised control trial found no adverse events related to either nicotine replacement therapy (NRT) or ENDS but did find that NRT users were more likely to report nausea (37.9% versus 31.3% of ENDS users) while ENDS users were more likely to report mouth or throat irritation (65.3% versus 51.2% of NRT users)