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Mobile phase gradients were 42% phase A at 0 min and hold for 9 min, increase to 55% in 7 min and hold for 2 min, increase to 90% in 1 min and hold for 6 min, decrease to 42% in 1 min and hold for 4 min

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The primary purpose of the filter is to reduce the tar and nicotine inhaled, but its worth noting that they do not eliminate all harmful substances