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Conclusion This review summarized the current literature highlighting the negative effects of MDM2p53 axis dysfunction in the context of hepatoma cells transformation (Table 2)

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Nationally, the rate was 8.8%.2 Other tobacco product use: Oklahoma E-cigarette and smokeless tobacco use in Oklahoma In 2017, 7.1% of adults used e-cigarettes and 7.4% used smokeless tobacco.3 In 2017, 16.4% of high school students in Oklahoma used electronic vapor products on at least one day in the past 30 days

Harmful chemicals such as formaldehyde and nicotine may reach be inhaled into the lungs while using such devices

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