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3 The effectiveness of these efforts is generally slow to emerge given the 20- to 30-year lag between smoking prevalence and lung cancer mortality, but positive changes are evident

22 By law, buyers have to be 18 or 21 In 2016, the FDA published rules and regulations for the sale of tobacco productsincluding e-cigarettesdeeming them to be subject to the Federal Food, Drug, and Cosmetic Act as amended by the Family Smoking Prevention and Tobacco Control Act, placing re strictions on their sale and distribution, and requiring warning statements on them

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