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Discussion Cigarettes are known to be highly toxic and can exert multiple effects on the pulmonary system, including, but not limited to, increases in apoptosis, inflammation, protease activation, DNA breaks as well as deranging the mucus clearance system 6

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It can result from various factors, including the withdrawal effects of nicotine and other chemicals found in cigarettes and physiological adjustments that the body undergoes as it adapts to smoke-free

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Pletcher MJ, Vittinghoff E, Kalhan R, et al