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Restraint - Health Concerns & Nicotine Addiction Most e-cigarettes contain nicotine, a highly addictive substance with well-documented harms, especially for adolescents and young adults

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Sir Richard (October 28, 1912 - July 24, 2005) and Sir Bradford Hill (July 8, 1897 - April 18, 1991) were among the first to suggest, in a study published in the British Medical Journal in 1950, that a cause and effect relationship existed between cigarette smoking and lung cancer

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Particularly in view of the higher prices charged for cigarettes nowadays, all these refinements are something of a triumph of merchandising