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Synphilin-1 then mobilizes SIAH1 to ubiquitinate mitochondrial proteins, recruiting LC3 as well as the lysosome marker Lamp1 to the mitochondria to initiate mitophagy (Fig

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Nearly a quarter of pregnant women say theyve been around secondhand smoke in their homes, at work, around a friend or relative which, according to new research, is linked to epigenetic changes meaning changes to how genes are regulated rather than changes to the genetic code itself in babies that could raise the risk of developmental disorders and cancer