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Since tobacco use is associated with several diseases that are also related to alcohol consumption (e.g., cancer, cardiovascular diseases, liver disease), it has become an example to emulate for communications purposes (31)

Source: University of Florida

Owing to concerns about variability in U-Cr values as a function of age, sex, race/ethnicity, and body size, it is recommended that the creatinine-adjusted concentration of an analyte for an individual be compared with a reference value obtained on a similar demographic group (e.g., adults with adults, children with children) [16]