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Asked about the tests, Sugimoto said he thought they would prevent non-smokers from joining the trial but added, I dont know whether they were done that rigorously. Told of Sugimotos doubts about the honesty of study participants, Eissenberg, who served on the FDAs tobacco products scientific advisory committee from 2011 to 2017, said it raises a great deal of concern. A principal investigator is required to make sure that the participants meet the inclusion-exclusion criteria that are in the protocol, said Eissenberg

Drug and Alcohol Dependence, 2019

Conversely, the duty revenue lost from illicit tobacco exceeds an estimated 3bn per annum [ix]

Smoking and vertical bone defects in a Saudi Arabian population

Smokeless tobacco, like chew, is notoriously linked to oral cancers, leukoplakia (pre-cancerous sores), and gum disease